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The Odoromics™ Company

At Yesse Technologies, we are building a technology platform that harnesses the biology of the real nose and merges it with cutting-edge nanotechnology to ultimately decode the last mystery of the senses.

“With Yesse, we are on our way to replace the no in nose with a convinced yes.”

─Dr. Charlotte D’Hulst, CEO       


We are on a mission to demystify the enigmatic sense of smell and to unveil a whole new world of data, Odoromics​™. 

We believe that our ground-breaking science can unleash the power of the nose to disrupt Flavor & Fragrance R&D pipelines and maybe one day put the nose in diagnose.


We are proud to be rooted in basic science and are employing what nature has fine-tuned for us ─through millions of years of evolution─ to measure smells with the precision of the human nose. Therefore, we are building an interdisciplinary team that shares our core values of integrity, thinking out-of-the box and pushing the boundaries of the unknown.


Yesse Technologies is headquartered at the Alexandria Center for Life Sciences, right at the heart of New York City’s vibrant and rapidly-growing biotech ecosystem, and has a subsidiary in Leuven, Belgium near its chip development partner imec.


The ORion21™ platform is the product of more than 30 years of fundamental research on the molecular biology of the sense of smell and is named after the constellation Orion (The Hunter), an acknowledgement to Hunter College (CUNY) where the technology was invented.

The science behind the technology has been extensively validated by Yesse’s co-founders, Drs. Paul Feinstein and Charlotte D’Hulst and has been published in the peer-reviewed journal Cell Reports in 2016.

“We employ what Biology engineered for us throughout evolution.”

─Prof. Paul Feinstein, CSO

We bring together a multidisciplinary team of dedicated scientists, engineers and entrepreneurs fueled by smart VCs and experienced advisors. 


“The people who are crazy enough to think they can change the world are the ones who do.“ 

─Steve Jobs


Co-Founder & CEO

Co-Founder & CSO

Managing Director, Europe

Our people

Principal Scientist

Manager of Operations

Senior Scientist

Board of Directors

Representing imec.xpand

Alexandria Venture Investments


We are funded by smart money and our investors are considered an essential part of our team.

Turning Nanotechnology into Business
Building the Future of Life-Changing Innovation™
New York, State of Opportunity

“If you can’t invent the future, the next best thing… is to fund it.”

John Doerr


The Michael J. Fox Foundation for Parkinson's Research
America's Seed Fund powered by NSF (NSF SBIR)
The City University of New York (CUNY)
VLAIO - Agentschap Innoveren & Ondernemen

To integrate the ORion21™ biology with state-of-the-art nanochip technology, we have partnered with R&D powerhouse imec (Belgium), the world-leading innovation hub in nanoelectronics and digital technologies.

UZ Leuven (Universitair Ziekenhuis Leuven)
Verhaert - Masters in Innovation
Accelerated by EIT Health
EIT Health is supported by EIT, a body of the European Union


January 19, 2021

Yesse Technologies secures another grant from The Michael J. Fox Foundation to sniff out Parkinson's disease. (Press release)

January 19, 2021
September 28, 2020

Yesse Technologies reaches an important milestone in its Parkinson’s program and presents second version of its Nose-On-Chip prototype. (Press release)

September 28, 2020
August 1, 2020

Yesse Technologies awarded with an Innovative Postdoctoral Entrepreneurial Research Fellowship (I-PERF) from the NSF.

August 1, 2020
May 1, 2020

Yesse Technologies receives 3 additional NSF SBIR grants to advance commercialization of the ORion21™ Platform (Phase IIb, TABA & TECP).

May 1, 2020
May 1, 2019

National Science Foundation awards $750,000 Phase II SBIR grant (Abstract & Press release)

May 1, 2019
March 22, 2019

MouSensor becomes Yesse Technologies, Inc., The Odoromics Company (Read more)

March 22, 2019
September 5, 2018

$3.3M Seed round closed led by imec.xpand & Alexandria Venture Investments (Read more)

September 5, 2018
July 30, 2018

Company establishes a Belgian subsidiary

July 30, 2018
July 14, 2018

Flanders Innovation & Entrepreneurship awards $1.2M grant

July 14, 2018
May 4, 2018

Michael J. Fox Foundation for Parkinsons’s Research awards $340,000 in follow-up funding (Read more)

May 4, 2018
June 12, 2017

National Science Foundation awards $225,000 Phase I SBIR grant (Read more)

June 12, 2017
May 11, 2017

CEO, Dr. Charlotte D’Hulst, wins Outstanding Pitch Award at NewYork Bio’s Annual Meeting

May 11, 2017
April 27, 2017

Michael J. Fox Foundation for Parkinson’s Research awards $100,000 pilot grant (Read more)

April 27, 2017
June 7, 2016

Core technology published in Cell Reports (Read more)

June 7, 2016
February 4, 2016

MouSensor (now Yesse Technologies) founded as a Delaware State Company

February 4, 2016

“All possibilities are on the other side of Yes. You have to have a Yes mindset to get to Greatness.”

─John C. Maxwell